Zyban® is a non-nicotine, prescription-only antidepressant medication. It was developed to treat depression, but it was later found to also help reduce the symptoms of nicotine cravings and withdrawal. Zyban has been shown to double the chances of a person quitting smoking after three months.

Zyban is often used by heavy smokers in conjunction with an NRT such as the patch or nicotine gum. Generally it is believed that Zyban is most effective if you begin to take it 1 or 2 weeks prior to your quit date. Typically, the average dose is 1 to 2 150 mg tablets per day.

Common side effects of Zyban include:

  • Weight loss
  • Dry mouth
  • Nausea
  • Difficulty sleeping
  • Dizziness
  • Sore throat
  • Constipation
  • Flatulence

Two notes on Zyban:

  • When prescribed for smoking cessation, it is called Zyban; when prescribed for treating depression, it is called Wellbutrin.
  • If you have a history of seizures, heavy alcohol use, serious head injury, bipolar (manic-depressive) illness, anorexia or bulimia, you should not take Zyban.

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